Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

A facile synthesis of 6-(1,3,4-oxadiazol-2-yl)-N-arylylpyridin-3-amines

Author(s): Venkataramana Medisetti and Umadevi Parimi*

5-bromopyridine-2-carbohydrazide (1) cyclised with Triethoxyorthophosphoricacid to form 5-bromo-2-(1,3,4- oxadiazol-2-yl)pyridine (2), which on reaction with triphenylpalladiumchloride offer 6-(1,3,4-oxadiazol-2-yl)-Narylylpyridin- 3-amine (3a-j).


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