Heracleum persicum, commonly known as Persian hogweed or golpar, is a flowering plant in the family Apiaceae, native to Iran. The aim of this study is to view its pharmacological effect and efficacy profiles. This review article was carried out by searching studies in PubMed, Medline, Web of Science, and IranMedex databases up to 2016.totally, of 116 found articles, 40 articleswere included. The search terms were “Heracleum persicum.”, “therapeutic”, “pharmacological”, “traditional medicine”. Various studies have shown that Heracleum persicum. Process Angiographic properties Antioxidantproperties, Anti-Candida Activity, Coronary angiography, Lipid profile,Infertility, Anti-inflammatory and analgesic properties, Anticonvulsantproperties. Heracleum persicum is widely used for therapeutic and purposes that trigger its significant value. Various combinations and numerous medicinal properties of its extract, essential oils, its stems and leaves demand further and more studies about the other useful and unknown properties of this multipurpose plant.