The phosphogypsum is an adsorbent which is used to remove heavy metals in aqueous media. The removal of lead by phosphogypsum was studied as a function of the contact time, the adsorbent dose and the adsorbate concentration. Phosphogypsum was prepared by wet process. The adsorption equilibrium of lead in the phosphogypsum is reached after 5 min and the absorption data have worked well at the Freundlich model. The maximum adsorption capacity of phosphogypsum was found to be 12.38 mg.g-1. The Equilibrium isotherms for the adsorption of Pb (II) were analyzed by the Langmuir, Freundlich, Temkin and Dubinin-Radushkevich models. The Freundlich isotherm model was found to represent better the data of Pb (II) sorption onto phosphogypsum. The results showed that the phosphogypsum is a suitable adsorbent for the removal of lead (II) ions from aqueous solutions.