Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

ß-Amyrin acetate of ethyl acetate extract of the bark plant artocarpus camansi and its antidiabetic activity

Author(s): Rosnani Nasution, Marianne and Hijjatin Nur

Isolation of chemical compounds from ethyl acetate extract of the stem bark of Artocarpus camansi (kulu) and antidiabetic activity test against male Swiss Webster mice using glucose tolerance has been done. Maceration with ethyl acetate of the bark A. camansi to yield concentrated ethyl acetate extract. Ethyl acetate extracts was obtained then separated by column chromatography to give fractions group A and fractions group B, the ethyl acetate extract also were characterized by GC-MS. The fraction group A then separated by column chromatography to give A isolate, the isolate was characterized by 1H-NMR, also was measured its activity to antidiabetic, while fractions group B was measured only its activity to antidiabetic. Based on analyses spectra MS and 1H-NMR suggested that the A isolate was ß-amyrin acetate. Test results antidiabetic ethyl acetate extract, fractions group A (contain A isolate) and fractions of group B at a dose of 50 mg fraction/kg bw respectively showed a decrease in blood glucose levels in the mice at 60th minutes to as much as 47 mg / dL; 59 mg / dL; 59.67 mg / dL and in the 90th minute was able to lower blood glucose levels of mice were 37.33 mg / dL, 43.33 mg / dL, 71.33 mg / dL


FIND ARTICLES
SCImago Journal & Country Rank
kız uzun zamandır masaj salonunda çalışıyor çok sulanan erkek oluyor ama porno izle bir türlü hiç birine vermiyor Ama sonunda genç paraya sıkışıyor ve bir porno resimleri sikiş için çok para teklif eden genç adama sonunda kabul ediyor ve evlerine giren amatör pornolar maskeli hırsız genç kadının odasındaki çekmecelerde para ararken kadının seksi iç sikiş çamaşırlarına denk geliyor Onları koklayarak yarağı taş gibi oluyor daha sonra genç porno fotoğrafları kadın odaya bir den bire girince hırsızı görüyor ve bağırmaya başlıyor Hırsız hızlıca porno hikayeleri kızın ağzını elleri ile kapatarak tam kızın kalçalarını kucağına alarak sevişiyor
ankara escort
mobile bitcoin casino
Casumo no deposit bonus bitcoin nedir?