Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


An eco-sustainable green approach for the synthesis of 2,6-naphthyridines under microwave irradiation

Author(s): K. P. Srivastava, Indu Singh, Anupma Kumari

A microwave-promoted new easy, efficient, clean and environmentally benign method for the synthesis of 2,6- naphthyridine and its derivatives from 4-cyano-3-pyridylacetonitrile has been developed. The desired products were isolated in excellent yields and high purity under eco-friendly conditions. The synthesized compounds were characterized by the IR, UV-Visible and 1H-NMR spectral analyses along with elemental analysis.

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