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An efficient and improved protocol for the N-arylation of N-heteroaryls using Ionic liquid as a reaction media | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

An efficient and improved protocol for the N-arylation of N-heteroaryls using Ionic liquid as a reaction media

Author(s): H. M. Meshram, B. Chennakesava Reddy, Palakuri Ramesh and N. Nageswara Rao

N-arylation of N-heteroaryls is described with aryl/ heteroaryl halides in the presence of CuI in ionic liquid [Bmim]BF4 as a reaction media. The reaction is very efficient and yields are very high. Moreover, the method is applicable for a variety of N-heteroaryls and Ionic liquid was recycled and reused.


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