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An efficient synthesis of formyl coumarins by microwave irradiation methodduff formylation | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

An efficient synthesis of formyl coumarins by microwave irradiation methodduff formylation

Author(s): Omprakash S. Chavan, S. B. Chavan and M. A. Baseer

A series of formyl derivatives of Coumarins have been synthesized by Duff formylation method, in this method hydroxyl Coumarins was reacted with hexamethylene tetramine (HMTA) in presence of tri-fluoroacetic acid (TFAA) under microwave irradiation techniques. The structures of all synthesized compounds were confirmed by IR, NMR, Mass and CHN analysis. This is a newly developed efficient synthesis of formyl Coumarins under microwave irradiation technique by Duff formylation method.


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