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An expeditious synthesis of riociguat, A pulmonary hypertension drug | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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Abstract

An expeditious synthesis of riociguat, A pulmonary hypertension drug

Author(s): Veerareddy Arava and Surendrareddy Gogireddy

Riociguat: A potent, Oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension, is prepared from commercially available 2-Chloronicotinic acid via (E)-2-(2-chloropyridin-3-yl)-2-(2-(2-fluorobenzyl) hydrazono) acetamide


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