Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Antioxidant and antibacterial activity of achyranthes aspera : An in vitro study

Author(s): Abi Beaulah G, Mohamed Sadiq A and Jaya Santhi R

Plants and plant-based medicaments are the basis of many of the modern pharmaceuticals we use today for our various ailments. The aim of the present study was to evaluate the antioxidant and antibacterial activities of the Achyranthes aspera plant extract in different organic solvents. The radical scavenging activity of the different extracts of root, stem, leaf and inflorescences was evaluated by DPPH assay and the antibacterial activity against Staphylococcus aureus a gram positive and Escherichia coli a gram negative bacteria was studied by Agar well cut diffusion method. All of the extracts exhibited different antioxidant and antibacterial activities and the activities varied from solvent to solvent and the activities are concentration and time dependant. The antioxidant and antibacterial activities were compared with the positive control Ascorbic acid and Gentamycin. A qualitative phytochemical analysis was carried out and found to possess bioactive compounds like alkaloids, glycosides, terpenoids, steroids, flavonoids, tannins.


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