Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Biospecific activities of rare earth complexes of hippuric acid and sulfanilamide

Author(s): Santwana Gaur and Kshamatha Joshi

The stability constants of some biospecific ligands (BHEB, BHETB, BHEAB) with the lanthanide ions determined potentiometrically reveals that the ligands have protons to dissociate and complexation occurs. The stability of metal complexes is expected to follow the order : Pr (III) < Nd (III) < Sm(III) < Gd (III) < Tb (III) < Dy (III) < Er (III). The complexes show antifungal and antioxidant activities.


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