Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Central core Uprolides a survey of some ring closing metathesis approaches

Author(s): O. Venkata Subba Raju and Y. V. Rami Reddy

The study of related to construction of central bicyclic core Uprolides D and E and the lactone fused to it mainly deals with the metathetic approaches. The 14-membered carbocyclic uprolides become excellent targets for RCM and ene-yne RCM with properly placing the diene and ene-yne systems.

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