Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Comparative Studies of Anti-inflammatory Activity In vivo and In silico Studies of 4-methoxy Benzoin and Benzoin

Author(s): Thanuja B, Ayyaddurai GK, kanagam CC

The Pharmacological activity of the synthesized benzoin (BEN) and 4-methoxy benzoin (4-MB) was studied and characterized by Mass, NMR, IR and single XRD analysis. Parent benzoin showed anti-inflammatory activity was evaluated by formalin induced paw oedema method. Introduction of additional methoxy group in the para position is found to more potent to have anti-inflammatory activity than parent benzoin. The results of the Pharmacological activity were comparatively studied using 1 EQG protein and that their activities were compared.


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