Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Eco-friendly synthesis of 1,2-dihydro-2,3-dimethyl-1-phenyl-4H-pyrazolo[4,3-e][1,2,4]triazin-5(6H)-one and 4-(2-(3,5-dimethyl-1H-pyrazol-4-yl)diazenyl)-1,2-dihydro-1,5-dimethyl-2-phenylpyrazol-3-one devoid of catalyst.

Author(s): E. Laxminarayana, T. Karunakar, B. Ravi Kumar and P. Venkat Reddy

The target molecules 1,2-dihydro-2,3-dimethyl-1-phenyl-4H-pyrazolo[4,3-e][1,2,4]triazin-5(6H)-one and 4-(2-(3,5- dimethyl-1H-pyrazol-4-yl)diazenyl)-1,2-dihydro-1,5-dimethyl-2-phenylpyrazol-3-one were synthesized by eco friendly microwave irradiation. The chemistry of the reactions employed in the synthesis of the target compounds together with their chemical behavior, are discussed and the structures of the newly synthesized compounds were confirmed by the IR and 1H-NMR and Mass spectral data.

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