Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Effect of Eucalyptus Camaldulensis Extracts on Leishmania major In Vitro and In Vivo

Author(s): Hind Mahdi Jarallah, Abdul Hussein Hubash, Abdul-Mohsin Hamed Jassim

The leaves extract of Eucalyptus camaldulensis (aqueous, alcoholic and oils) were studied as antileishmanial inhibition on Leishmania major promastigotes form. Oils were more active against promastigotes than aqueous and alcoholic extract, thus, the LD50 for oils, alcoholic and aqueous extract was (0.602, 3.630 and 4.786) mg/ml respectively. Oils and alcoholic extract were used by topical application for treated BALB/c mice experimentally infected with L. major, on the footpad thickness and mice tail base ulcers.


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