Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Efficient one-pot synthesis of multi-substituted tr iazolopyrimidines by using DBU as basic catalyst via MCR’s

Author(s): Hymavathi Alluri, Haritha Gonthina, Ravi Kumar Gant a, Madhu Ch and Venkateswara Rao. B

One-pot synthesis of various [1, 2, 4]-triazolo [4, 3-a] pyrimidine derivatives from condensation of 3 -amino-[1, 2, 4]-triazole, malononitrile and aryl aldehydes using DBU in ethanol under reflux. The targeted molecule s are obtained in better yields and take lower reaction t imes.

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