Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Facile synthesis of 8-methyl-4H-furo [2,3-h] isoflavones

Author(s): Noor Shabana, K. Dayananda Reddy

7-Hydroxyisoflavones (1a-e) with allylbromide refluxed for 6 hrs to give7-alloxyisoflavones (2ae) and their Claisen rearrangement to 8-allyl-7-hydroxyisoflavones (3a-e) with react dichlorobis palladium in benzene for 30 min at room temperature to give 8-methyl-4H-furo [2,3-h] isoflavones(5a-e )

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