Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Go Green-Effective Synthesis of Isatin Containing Oxadiazole Moiety Based on Microwave-Assisted Heating Protocol

Author(s): Shradha Pandey, Prateek Pandey, Jagdamba Singh

An efficient microwave heating methodology for the synthesis of Isatin containing oxadiazole moiety is reported. Each compound was obtained with high yield and purity in a few minutes. The synthesized compounds (7a-d) were characterized using Infra-Red (IR), Proton Nuclear Magnetic Resonance (1H-NMR) and mass spectra. Comparison with conventional synthesis indicated the enhanced yield with faster reactions under microwaves.


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