Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Microwave Promoted Synthesis of Pharmacologically Active Pyrazolidinonyl Derivatives of Benzothiazoles

Author(s): Krishnakant T Waghmode, Prachi K Shinde

Microwave promoted synthesis of pharmacologically active N-(1,3-benzothiazol-2-yl)-2-[(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino]acetamides is described. Microwave assisted synthesis not only reduced the reaction time drastically but also gave excellent yields. The synthesized compounds are characterized by Fourier Transform Infra-Red (FTIR), Proton Nuclear Magnetic Resonance (1H-NMR) and mass spectral data.


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