Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Polyaniline sulphate salt catalyzed synthesis of amidoalkyl naphthols under solvent free conditions

Author(s): Narasimha Murthy Kotra, Buchi Reddy Reguri, Mukkanti Khagga

An alternative synthesis of amidoalkyl naphthols, employing a three-component condensation reaction of β- naphthol, aromatic aldehyde, amides or urea in the presence of polyaniline sulphate salt under solvent free conditions has been described. The present procedure offers advantages such as shorter reaction time, simple workup, excellent yields, recovery and reusability of catalyst

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