Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Reversed-phase high-performance liquid chromatography of disaccharides labeled by 4-aminobenzoic acid ethyl ester

Author(s): Toratane Munegumi* and Akito Goto

Disaccharides and oligosaccharides are important as the units of structure of polysaccharides and as molecules that associate with glycoproteins and glycolipids. This research addressedthe high-performance liquid chromatography (HPLC) analysis of disaccharides labeled by 4-aminobenzoic acid ethyl ester (ABEE) on a reversed-stationary-phase column. The results of this study demonstrated the successful resolution of ABEE-labeled disaccharides and their UV detection at 305nm.


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