Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry
ISSN: 0975-413X
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Abstract
Solid fly-ash: H2SO4 is an efficient catalyst for cyclization of alpha,Beta-unsaturated ketones: Solvent-free synthesis of some oxazine amine derivatives
Author(s): G. Thirunarayanan and K. G. Sekar*Attempts to synthesis some aryl oxazine amines [5,6-dihydro-4-aryl-6-(substituted phenyl)-2H-1,3-oxazin-2-amines] by fly-ash:H2SO4 catalyzed solvent-free cyclization of aryl chalcones and urea under microwave irradiation. The yield of the oxazines were more than 85%. These oxazine imines were characterized by their physical constants and spectroscopic data.
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