Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Structural, thermal and antifungal activity studies of isomeric Sm(III) Juglonates

Author(s): Pritamkumar V. Shinde and Mrudula P. Wadekar*

Sm(III) chelates of lawsone(LW: 2 hydroxy 1,4 napht hoquinone), juglone(JU: 5 hydroxy 1,4 naphthoquinon e), phthiocol(PH: 2 hydroxy, 3 methyl 1,4 naphthoquinon e) and plumbagin(PL: 5 hydroxy, 2 methyl 1,4 naphthoquinone)which are called as Sm(III)juglonate s, are studied by using Far IR, XRD and SEM. Kineti c parameters of the chelates are reported by using Co ats and Redfern equation. Antifungal activity of th e chelates against S. Cerevisiae, A. Flavus and C. Albicans is studied and the results are compared within isom eric pairs of chelates.


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