Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Studies on schiff bases from methyl-1-naphthyl ketone. Part-II: Synthesis and characterization of ketimines from 1-acetylnaphthalene with derivatives of aniline

Author(s): C. J. Patil, Manisha C. Patil Mrunmayee C. Patil and R. G. Mahale

The Ketimines (Schiff bases) were prepared from Methyl-1-naphthyl-ketone with Aniline, 2-Chloro-aniline, 3- Chloro-aniline, 4-Chloro-aniline and 2-Nitroaniline using toluene as solvent by azeotropic(reflux) method using Dean and Stark. The synthesized ketimines were characterized and confirmed by colour, physical constant, TLC and spectral(UV-Vis and FTIR) information.

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