Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Synthesis and antibacterial activity of some 5-[(2’,6’-dinitro-4’-trifluoromethylphenoxy)-4”-methylphenyl)-2’(phenyl)]-benzothia-4”-methylphenyl)-2-(phenyl)]-benzothiazepine

Author(s): H. D. Jahangirpuria, H. B. Naik, C. G. Patel and S. A. Makwana

5-[(2’,6’-Dinitro-4’-trifluoromethylphenoxy)-4”-methylphenyl)-2’(phenyl)]-benzothia-4”-methylphenyl)-2- (phenyl)]-benzothiazepine have been synthesized by the condensation of 5-[(2’,6’-Dinitro-4’- trifluoromethylphenoxy)-4”-methylphenyl)-2’(phenyl)]-benzothia-4”-methylphenyl)-2-(phenyl)]-benzothiazepine” chalcone with o-amino-thiophenol.These compounds were screened for antibacterial activity against S.aureus and E.coli.


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