Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Synthesis and antimicrobial evaluation of thioglucosides and acyclic Cnucleosides of 2-methylbenzimidazole

Author(s): Adel A. H. Abdel-Rahman, Ibrahim F. Nassar, Ibrahim M. H. El-Kattan, Aly A. Aly, Mohamed S. Behalo and Nayera A. M. Abdelwahed

Some thioglucosides and acyclic C-nucleosides of 2-methyl-1H-benzimidazol were newly synthesized. The structures of the products were confirmed by different spectral analyses and some of the newly synthesized compounds were evaluated for their potential antimicrobial activity against Gram+ve and Gram–ve bacteria as well as some fungi which show good activity.


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