Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Synthesis and biological evaluation of indoles

Author(s): Subba Rami Reddy S. R.*, Suryanarayana Rao V. and S ubba Narayana Kanchana

ndole ring system is the most important heterocycl e in nature have an important structural importance in many pharmaceutical agents. Indole nucleus has antimicro bial activities. Objective of this research is to s ynthesize and characterization of indole derivaties. Different ki nd of indole ring derivaties were synthesized such as 3-((E)-2- nitrovinyl)-1H-indole 16; 2-(1H-indol-3-yl)ethanamine 17; N-(2-(1H-indol-3-yl)ethyl)benzamide 18; methyl 2-(3- (2-(benzamido)ethyl)-1H-indol-1-yl)acetate 19; Synyhesis of 2-(3-(2-(benzamido)ethyl)-1H-indol-1-y l)acetic acid 20; N-(2-(1-((2,3-dihydro-1H-inden-5-yl carbamoyl) meth yl)-1H-indol-3-yl)ethyl)benzamide 21.


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