GET THE APP

Synthesis and Characterisation of Fingolimod Impurities: A Drug for Multiple Sclerosis | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis and Characterisation of Fingolimod Impurities: A Drug for Multiple Sclerosis

Author(s): Maruthi Raju N, Venkateswara Rao B, Siddaiah V

Fingolimod (1) is an immunomodulating drug, frequently used for treating Multiple Sclerosis (MS) approved by the US-FDA. During the process development of Fingolimod, some process related impurities were observed along with the final API. These impurities were identified as N,N-dimethyl (2), N-methyl (3), nitromono methyl (4), monomethyl (5), nitrohydroxy (6) and hydroxy (7) impurities. The present work describes the synthesis and characterization of these impurities.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry