Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Synthesis and characterization of novel benzimidazole chalcones as antibacterial agents

Author(s): Gopal K. Padhy1,2, Jagadeesh Panda3 and Ajaya K. Behera1*

Efficient synthesis of some new N-Benzyl substituted benzimidazole chalcone derivatives were performed by multistep reaction sequences. The synthesized compounds were characterized using IR, 1H NMR, mass spectrometry and elemental analysis. The synthesized compounds were screened for their antibacterial activity against selective gram positive and gram negative bacteria. Compound 10 was found to be most active among the series.


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