GET THE APP

Synthesis and study of chlorosubstituted 4-aroyl/alkoyl pyrazoles and isoxazoles and their impact on phytotic growth of some vegetable crop plants | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis and study of chlorosubstituted 4-aroyl/alkoyl pyrazoles and isoxazoles and their impact on phytotic growth of some vegetable crop plants

Author(s): C. L. Deotalu and P. R. Rajput

Aroyl/alkoylacetophenones (2a-b) undergoes intramolecular claisen condensation to form 1-(2’- hydroxy-3’,5’-dichlorophenyl)-3-aryl/alkyl-1,3-propanediones (4a-b) which on treatment with aromatic and aliphatic aldehydes in ethanol containing little piperidine forms 3-aroyl/alkoylchromanones (5ab) subsequently 3-aroyl/ alkoylchromones (6a-b). 3-Aroyl/alkoylchromones (6a-b) on treatment with Ph.NH.NH2.HCl in DMSO containing small amount of piperidine gave 4-aroyl/alkoylpyrazoles (7a-b).So also 3-aroyl/alkoylchromones (6a-b) on treatment with NH2OH.HCl in DMSO containing a small amount of piperidine gave 4-aroyl/ alkoylisoxazoles (8a-b). The structures of newly synthesized chlorosubstituted 4-aroyl/alkoyl- pyrazoles (7a-b) and 4- aroyl/alkoylisoxazoles (8a-b) were elucidated on the basis of molecular weight, elemental analysis and their spectral data.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry