GET THE APP

Synthesis, Characterization and Antimicrobial Studies on Some Pyridoxylidene-sulphamethoxazole Schiff Base Tellurium (IV) Complexes | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission Systemof respective journal.

Abstract

Synthesis, Characterization and Antimicrobial Studies on Some Pyridoxylidene-sulphamethoxazole Schiff Base Tellurium (IV) Complexes

Author(s): Deepak Sonu Chauhan, Krishna K Verma, Sapana Garg

A monobasic bidentate Schiff base Pyridoxylidene-sulphamethoxazole (HPL-SMZ) synthesized from sulphamethoxazole and pyridoxal, form complexes with aryltellurium (IV) trichlorides and diaryltellurium (IV) dichlorides of the type PL-SMZ.RTeCl2 and PL-SMZ.R2TeCl (R=4-methoxyphenyl, 4-ethoxyphenyl, 4-hydroxyphenyl and 3-methyl-4-hydroxyphenyl). They have been characterized by elemental analyses, molar conductance, Fourier Transform Infrared Spectroscopy (FTIR) and Proton Nuclear Magnetic Resonance (1HNMR) spectroscopy. The spectral studies predict the coordination of tellurium through phenolic oxygen after deprotonation and nitrogen of the azomethine group, thus giving pentacoordinated tellurium (IV) complexes probably in a distorted trigonal bipyramidal environment. The complexes were evaluated for their antifungal and antibacterial activities and observed to be more active as compared to parent Schiff base and aryltellurium chlorides.


PDF

Select your language of interest to view the total content in your interested language

30+ Million Readerbase
SCImago Journal & Country Rank
Google Scholar citation report
Citations : 25868

Der Pharma Chemica received 25868 citations as per Google Scholar report

Der Pharma Chemica peer review process verified at publons
Der Pharma Chemica- Journals on pharmaceutical chemistry