Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Synthesis, characterization and biological activity of some new 5- halo-4, 6-dimethoxy-2-(alkoxy or aryloxy) pyrimidines

Author(s): A. S. Paniraj,*a,b K. M. Lokanath Rai,a Prasanna V Bhat,b P. Sanath Kumar Goud,b S.G.Vadiraj b, Prosenjit Boseb and N. Suchetha Kumari c

New 5-halo-4, 6-dimethoxy-2-(alkoxy or aryloxy) pyrimidines (4a-r) were prepared from 5-halo- 4,6-dialkoxy,2-methylsulfonylpyrimidine. The structure of newly synthesized compounds was characterized by their spectral date. The newly synthesized compounds were evaluated for their anmicrobial and antifungal studies. Some of the compounds showed moderate to good activity.


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