Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Synthesis, characterization and biological applications of poly meta amino phenol and its nano compound

Author(s): Thenmozhi G, Jaya Kumar D, Mohanraj Gopalswamy and Jaya Santhi R

The polymer and the nano compound of meta aminophenol was prepared by oxidative chemical polymerization in acidic medium using potassium dichromate as an oxidant at 00C and they were characterized by FT- IR, UV-VIS, SEM, TEM, TGA and DSC. The conductance was measured and found to be semiconducting in nature. From the thermal analysis it is evident that the poly nano compound is thermally more stable than the corresponding polymer. The resulting polymer and its nano compound were analyzed for its antioxidant activities using DPPH assay and the antibacterial activities were measured by agar well cut diffusion method against two bacterial stains Staphylococcus aureus (gram +ve) and Escherichia coli (gram -ve). From the result it is evident that the antioxidant and antibacterial activities of poly meta aminophenol nano compound were greater than the corresponding polymer and they were concentration and the time dependant. The increased activities of poly nano compound may be due to its smaller size which increases the surface area and these properties can be considered in the field of biomaterials in biomedical areas.


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