Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Synthesis of 11,12-dimethoxy-9-p-toluene sulphonyl-6,7,8,9-tetrahydro-5Hbenzo[2,3]azepino[5,4-c]quinolin-5-one using MCM-41(H)

Author(s): Srinivasa Reddy Konda, Buchi Reddy Reguri, Mukkanti Kagga

The development in the benzazepine field for medicinal interests, attention has been paid almost exclusively to substituent changes, with the adjustment of open chain and cyclic groups attached to both the aromatic and the azepine ring. In some instances the benzene ring has been replaced with other aromatic ring systems, e.g. Indoles1,2 which is particularly true in the benzodiazepine field. Herein, we report the New Synthesis of 11,12-dimethoxy-9-(4- phenylsulphonyl)-6,7,8,9-terahydro-5H-benzo[2,3]azepino[5,4-c]quinolin-5-one.

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