Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Synthesis of 3(n(1,3dioxo 1H benzo[de]isoquinolin-2(3H)-yl)alkyl)-2-(4- substituted) phenylthiazolidine-4-carboxylic acid.

Author(s): J. Ramchander

Regioselective synthesis of 3(n(1,3dioxo1Hbenzo[de]isoquinolin-2(3H)-yl)alkyl)-2-(4-substituted) phenylthiazoli dine-4-carboxylic acidwere performed by coupling of 2-aryl-thiazolidin-4-caboxylic acids respectively with N-(ω- bromoalkyl)-1,8-naphthalimideusing K2CO3 in DMF medium. The structure of all the new compoundswere characterized by IR, 1H-NMR, 13C-NMR, and Mass spectral data.


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