Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Synthesis of 5-(3-aryl-1-phenyl- 1H -pyrazol-4-y1)- 1H -tetrazole by using AgNo 3 catalyst

Author(s): Ch. Madhu*, G. Ravikumar, G. Raju, K. Raja, A. Hyma vathi, G. Haritha, S. Hari Prasad, M. Padma and B. Venkateswara Rao

An efficient and convenient method has been develop ed for the synthesis of 5- (3-Aryl-1-Phenyl-1H – Py razol-4-y1)- 1H-tetrazoles form the (3+2) cycloadition of 3-Aryl -1Phenyl-1H – pyrazole -4- carbonitrile with sodium azide using AgNo 3 as a catalyst. The corresponding 5-(3-Aryl-1–pheny l-1H-pyrazol-4-y1)-1H –tetrazoles were formed in go od yields.

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