Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Synthesis of aryl 2-oxazolines from aromatic nitriles and aminoalcohols using magnetically recoverable Pd/Fe3O4

Author(s): Aviraboina Siva Prasad and Bollikonda Satyanarayana

This paper describes the synthesis of aromatic 2-oxazolines from aromatic aldehydes and 2- aminoalcohols using magnetically recoverable Pd/Fe3O4. This method is found to be applicable for wide range of aromatic nitriles and amino alcohols. High catalytic activity and ease of recovery using an external magnetic field are additional eco-friendly attributes of this catalytic system. The catalyst was recycled for five times without significant loss of catalytic activity.


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