Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Synthesis of Isoxazolyl-benzenesulfonamide derived from N -[4-(2,3-dibromo-3-aryl-propanoyl)-phenyl]benzenesulfonamide

Author(s): Hemant S. Chandak

N-[4-(2,3-dibromo-3-aryl-propanoyl)-phenyl]benzenesulfonamide on reaction with hydroxylamine hydrochlorde in ethanol in presence of catalytic amount of piperidine afforded N-(4-(5-arylisoxazol-3- yl)phenyl)benzenesulfonamides. Under microwave irradiation, reaction proceeds smoothly in ethanol without using piperidine. The reaction time was 4-5 minutes and yields were better. The synthesized compounds are characterized by elemental analysis, IR, 1H NMR and Mass spectral data.


ankara escort
mobile bitcoin casino
Casumo no deposit bonus bitcoin nedir?