Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

Synthesis of pyranopyrazoles by using eco-friendly montmorillonite K-10 catalyst-their antioxidant and antimicrobial assays

Author(s): G. Raveendra Reddy, V. Hanuman Reddy, T. Veera Reddy and K. Naresh

Eco-friendly montmorillonite K-10 reusable catalyst mediated three-component reaction in aqueous and organic medium at room temperature has been developed for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives and studied their biological properties. The compounds 4d, 4c and 4h showed excellent antioxidant activity. All the compounds exhibited higher antibacterial activity towards Gram-negative Escherichia coli bacteria. The compound 4f exhibited antifungal activity almost equal to the standard drug.


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