Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Synthesis of substituted-4, 6-diaryl-2-imino-diphenyl-6H-1, 3-thiazines

Author(s): Aprana. S. Dighade and Surendra. R. Dighade

Six different Chalcones I(a)-I(f ) were synthesized by condensing 2-hydroxy-3-iodo-5-methyl acetophenone with six different aromatic aldehydes in ethanol using NaOH. These chalcone were cyclized with diphenyl thiourea in ethanol yielding IIa – IIf . The synthesized compounds were characterized by I.R., NMR spectral analysis.

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