Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry

Abstract

The determination of the amount of some heavy metal s in edible clay of Enyigba village in Abakaliki Ebonyi State, Nigeria

Author(s): S. P. I. Ogah and I. I. Ikelle

This work involved the analyses of elemental conten t of edible clay and investigation of the kinetics of some of the detected elements in tissues and blood of rabbits. The clay sample was collected from Enyigba village in Abakaliki, Ebonyi State of Nigeria and only metallic elements were determined in the clay and the detected elemen ts kinetically investigated. The analysis of edible clay obtained was carried out using Atomic Absorption Spectroscop y (AAS). They include Pb, Cd, Cu, Zn, Ba, Mn, Ca, Ni, Na, Mg , K, Fe, As, Co and Cr. The results showed the pres ence of essential metallic elements, trace elements and tox ic heavy metals in the clay. The administration of the edible clay to rabbits orally resulted in the absorption and di stribution of Ca, Mg, K, Na, Cu, Ni, Fe and Mn to t he various organs and tissues of the body. The absorbed elemen ts were still present in the organs and tissues of the body 10 days post administration, showing that the elements were widely distributed in the body, with increase d half-lives.


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