Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry and Computational Chemistry


Transition-metal-free double C-S cross-coupling reaction by using Na2S as a sulfurating reagent

Author(s): Satish P. Nikumbh a,b , V. Narayana Murthy a , T. Srinivasa Rao a , Y. Chiranjeevi a , Suju C. Joseph a,b , Y. L. N. Murthy b and Akula Raghunadh a *

A highly efficient synthesis of N-substituted indolo[3',2':4,5]thieno[2,3-b]quinoxaline derivativ es via double C−S cross-coupling reaction. The odorless and stable so lid Na 2 S was used as a suitable and environmentally friend ly source of sulfur. The double C−S bonds have not pre viously have been achieved, which renders our obser vation more striking.

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