Synthesis, characterization and antimicrobial activities of 4-Benzylidene-1-{4-[3-(substituted phenyl)prop-2-enoyl]phenyl}-2-phenyl-imidazol-5-one
By R. A. Shah, P. S. Patel, D. K. Trivedi, P. J. Vyas
ABSTRACT
Some 4-benzylidene-1-{4-[3-(substituted phenyl)prop-2-enoyl]phenyl}-2-phenyl-imidazol-5-one were synthesized by the condensation of 1-(4-acetylphenyl)-4-benzylidene-2- phenyl- imidazol-5-one with various aldehydes. The intermediate 1-(4-acetylphenyl)-4-benzylidene-2- phenyl- imidazol-5-one was synthesized by the condensation of 4-benzylidene-2- phenyl -1,3-oxazol-5-one with 1-(4-aminophenyl) ethanone in presence of pyridine. The products were characterized by spectral and analytical data. Most of the tested compounds showed promising antibacterial and antifungal activity.
Keywords : Synthesis, substitutedChalcones, substitutedphenyl, Oxoimidazoline.
