Microwave synthesis and antimicrobial activity of some N-aryl hydrazones

 

 

By Bharat Parashar, Sudhir Bharadwaj, Vinod K. Sharma, Pinki B. Punjabi

 

ABSTRACT

 

-N-arylhydrazone derivatives of N-phenyl anthranilic acid are pharmacologically active and are very useful. A number of hydrazide derivatives have been synthesized by the   condensation of the hydrazide with the numbers of aromatic aldehydes and ketones in the presence of conc. hydrochloric acid as a catalyst. The reactions have been carried out under microwave irradiation.  The structures of the products were confirmed by physico-chemical and spectral data like IR, NMR and Mass. 

 

 

 

Keywords : N-phenyl anthranilic acid, hydrazone, hydrazide, microwave.

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