An efficient one-pot synthesis of 2, 4, 6-triaryl pyridines and their in vitro antimicrobial activity
By Bhaskar S. Dawane, Shankaraiah G. Konda and Raghunath B. Bhosale
ABSTRACT
The analytical methods of qualitative and quantitative determination of ions in solutions are very flexible to automation. In this research by using a computer simulation a potentiometric titration of bromide and chloride ions by nitrate solution of some monovalent cations with pH glass electrode has been done. A proper reagent called mediator is added to the medium that in end point of the reaction will develop an intense change in pH. So, pH electrode indirectly becomes sensitive to the changes of cations concentration (titrant). The results show that, the added reagent to the medium should be a weak acid so that its conjugate base creates a less soluble precipitate with titrant cation by approaching to the end point of the reaction.
Keywords : Precipitation titration, computer simulation, mathematical modeling pH, electrode.
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