Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


2-[Benzyl(methyl)amino]propanedinitrile-New Building Block for Synthesis of Riociguat, a Pulmonary Hypertension Drug

Author(s): Kristine Nerkararyan, Karine , Nairi Gasparyan, Mariam Gharibyan, Mikayel Movsisyan, Frank Porstmann

Riociguat is a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension, is prepared via an efficient, non-infringing synthesis route from commercially available diethyl malonate via [N-Methyl(benzyl)amino]propanedinitrile.

Full-Text PDF

SCImago Journal & Country Rank
Recommended Conferences
bornova escort karşıyaka escort osmangazi escort buca escort anne porno fetiş porno anal porno bartın escort burdur escort eskişehir escort escort izmir bursa escort porno escort bayan