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A Catalyst Free Simple and Efficient One Pot Syntheis of N-Benzyloxazolidinoe Derivatives | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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Abstract

A Catalyst Free Simple and Efficient One Pot Syntheis of N-Benzyloxazolidinoe Derivatives

Author(s): Rapolu Venkateshwarlu, Satish P. Nikumbh, Rajesh Jinkala, Vidavalur Siddaiah, Shambhu Nath Singh, Hindupur Ramamohan, Akula Raghunadh

An efficient and catalyst free one pot synthesis of N-benzyloxazolidinone derivatives is developed by reaction of N-benzyl-β-amino alcohol derivatives and N, N-carbonyldiimidazole (CDI) in DMSO. A range of novel N-benzyloxazolidinone derivatives were synthesised by using this one pot methodology with good to excellent yields.


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