Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

A Facile and an Efficient Synthesis of Baylis-Hilman Adducts via Vinylalumination of Isatins

Author(s): Rajitha Galla, Sasikala Maadwar, Arupula SanjeevaKumar

A highly efficient synthesis of Baylis-Hilman derivatives has been achieved via a vinylalumination of isatins at room temperature. The resulting oxindole scaffolds were obtained in moderate to high yields. The main advantages of this manuscript are short reaction time, operationally simple, purification of products by non-chromatographic method.


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