A microwave assisted synthesis of few 7-mercaptobenzimidazolyl fluoroquinolones | Abstract

Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

ISSN: 0975-413X
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A microwave assisted synthesis of few 7-mercaptobenzimidazolyl fluoroquinolones

Author(s): M. Jeyanthi* and B. R. Venkatraman

A series of new 7-mercaptobenzimidazolyl fluoroquinolone compounds (3a-e)were synthesized using microwave irradiation technique starting from (3S)-9, 10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4- ij]quinoline-6-carboxylic acid. The structures of the synthesized compounds were established on the basis of their spectral and analytical data and were found in good agreement with that of the compounds obtained by conventional chemical methods.


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