Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

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A new insight into Beckmann rearrangement for the synthesis of some ( E )-3- arylidenepiperidin-2-ones

Author(s): Satbir Mor and Preeti Pahal

Synthesis of some (E)-3-arylidenepiperidin-2-ones ( 7 ) derived from cyclopentanone ( 1 ) via thionyl chloride/dry dioxane mediated Beckmann rearrangement in moderate yields has been reported. The structural confirmat ion of the synthesized compounds was carried out on the ba sis of spectral (IR, NMR and mass) as well as eleme ntal analysis results.


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