Der Pharma Chemica
Journal for Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Sciences and Computational Chemistry

Abstract

A Review on Hypertensive Analytics

Author(s): Navneet Singh

Due to changed life style, sustained arterial hypertension triggers the possible damage of blood vessels in kidney, heart, and brain, and leads to an increased incidence of renal failure, coronary disease, cardiac failure, and stroke. Hypertension is a cause of morbidity and mortality, worldwide. This review presents a comprehensive overview on three dimensional study of hypertension within the analytics of mechanism, management and the potent heterocyclic moieties for the antihypertensive activity. The antihypertensive derivatives of moieties azitidinone, imidazole, indole, oxadiazole pyridine, quinazoline and thiadiazoles have been covered.


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